Spravato in Colorado Springs, CO: Receive Real Relief
Understanding Spravato: What You Need to Know
Spravato, the trade name for esketamine, is a relatively new treatment option for individuals diagnosed with treatment-resistant depression (TRD). Approved by the U.S. Food and Drug Administration (FDA) in 2019, Spravato offers hope to those who have not found relief with traditional antidepressants.
Unlike conventional medications that typically take weeks to show improvement, Spravato in Colorado Springs, CO, can provide rapid symptom relief, often within hours. This fast-acting nature makes it a groundbreaking option for those who have been struggling with depressive episodes for years.
Esketamine, the active ingredient in Spravato, is a derivative of ketamine—a compound long used as an anesthetic. Administered as a nasal spray, Spravato is used in conjunction with an oral antidepressant, providing a two-pronged approach to tackling depression symptoms.
This innovative treatment at Southern Colorado TMS is not just another medication; it represents a shift in how depression is approached and managed. By targeting different pathways in the brain, Spravato offers a new lease on life for those who have felt trapped by their condition.
Who Can Benefit from Spravato in Colorado Springs, CO?
Spravato is specifically indicated for adults with treatment-resistant depression, meaning those who have tried at least two different antidepressant treatments at adequate doses and durations without sufficient improvement. For many, Spravato represents a last-ditch effort after years of battling depression with no success from traditional methods.
In addition to TRD, Spravato has also shown promise in treating other types of depressive disorders, including major depressive disorder (MDD) with suicidal ideation. By providing swift relief, Spravato can stabilize mood and reduce the immediate risk, allowing patients to work on longer-term strategies for managing their mental health.
A thorough evaluation by a qualified healthcare provider is necessary to determine if Spravato is a suitable option.
The Science Behind Spravato and Its Effectiveness
Spravato works differently from traditional antidepressants, which usually target neurotransmitters like serotonin, norepinephrine, and dopamine. Instead, esketamine affects the brain’s glutamate system.
Glutamate is the most abundant neurotransmitter in the brain, playing a key role in synaptic plasticity, which is critical for learning and memory. By modulating this system, esketamine helps to restore synaptic connections in brain regions involved in mood and emotional regulation.
Clinical studies have demonstrated the efficacy of Spravato in reducing depressive symptoms in patients with TRD. In one pivotal trial, approximately 70% of participants showed a significant reduction in symptoms within 24 hours of their first dose.
Long-term studies have also indicated that continued use of Spravato, in combination with an oral antidepressant, can sustain these improvements over time. These findings underscore the potential of Spravato in Colorado Springs, CO, to not only provide immediate relief but also maintain mental health stability in the long run.
A Multi-Treatment Approach to Spravato in Colorado Springs, CO
One of the most powerful aspects of Spravato therapy is its ability to work alongside other treatments to enhance outcomes for individuals with treatment-resistant depression. When combined with approaches like medication management, ketamine therapy, and transcranial magnetic stimulation (TMS), Spravato can play a vital role in creating a personalized, comprehensive care plan.
Spravato’s fast-acting nature makes it especially valuable as a complement to other therapies. While ketamine therapy also provides rapid symptom relief, Spravato offers the convenience of a nasal spray and is FDA-approved for treatment-resistant depression. Used in coordination with ongoing psychiatric care and evidence-based treatments, Spravato can help patients achieve greater stability, improve quality of life, and engage more effectively in long-term healing.
TMS
Transcranial Magnetic Stimulation (TMS) is a non-invasive treatment that uses magnetic pulses to stimulate brain areas involved in mood control, helping relieve symptoms of depression.
TMS
Transcranial Magnetic Stimulation (TMS) is a non-invasive treatment that uses magnetic pulses to stimulate brain areas involved in mood control, helping relieve symptoms of depression.
Ketamine Therapy
Ketamine therapy offers rapid relief from severe depression, anxiety, and PTSD by targeting brain receptors differently, making it effective for those unresponsive to traditional treatments.
Ketamine Therapy
Ketamine therapy offers rapid relief from severe depression, anxiety, and PTSD by targeting brain receptors differently, making it effective for those unresponsive to traditional treatments.
Medication Management
Medication management involves evaluating, prescribing, and adjusting psychiatric medications to ensure effectiveness, minimize side effects, and support overall mental health and treatment goals.
Medication Management
Medication management involves evaluating, prescribing, and adjusting psychiatric medications to ensure effectiveness, minimize side effects, and support overall mental health and treatment goals.
Southern Colorado TMS NOW OFFERS COVERAGE FOR SPRAVATO (ESKETAMINE)
Safe & Comfortable Spravato
The Spravato Treatment Process: What to Expect
Comprehensive Assessment
Undergoing Spravato treatment involves more than just receiving a prescription. The process is carefully monitored to ensure safety and efficacy. The initial evaluation includes a comprehensive assessment of medical history, current medications, and previous treatments to confirm eligibility.
Spravato Treatment
During the treatment session, the patient self-administers the nasal spray under the guidance of a healthcare professional. The initial dosing phase typically involves twice-weekly sessions for the first four weeks. Each session lasts about two hours, and the patient is observed to ensure they can safely leave the facility after the session.
Monitor & Follow-Up
Following the initial phase, the frequency of Spravato treatments in Colorado Springs, CO may be reduced to once a week or once every two weeks, depending on the individual's response. Continuous monitoring and follow-ups are essential to assess the treatment's effectiveness and make any necessary adjustments.
Do you believe that you suffer from depression or anxiety? Check out our online assessments for a quick online self-assessment to see if you suffer from a mental health related issue and to see if you could benefit from Spravato treatment.
FAQ
Spravato® is considered safe when administered in a certified medical setting under strict supervision. Colorado Springs patients are carefully screened before treatment to ensure it is medically appropriate.
Blood pressure and vital signs are monitored before, during, and after each session, which typically lasts about two hours. Temporary side effects such as dizziness, dissociation, or nausea are common and usually resolve the same day.
Many Colorado Springs patients notice improvements in mood, clarity, or suicidal thinking within hours or days of their first Spravato® session.
Unlike traditional antidepressants, which may take weeks to work, Spravato® offers rapid relief that can be especially important for severe or treatment-resistant depression.
Spravato® is intended for adults with treatment-resistant depression who have not improved after trying at least two antidepressant medications.
A thorough evaluation reviews medical history, current medications, and symptom severity to ensure safety and suitability.
Patients often describe feeling temporarily disconnected, relaxed, or introspective during treatment. Some experience lightheadedness or changes in perception.
These effects are expected and monitored throughout the session. Most patients feel grounded by the end of the observation period, and a ride home is required for safety.
Yes. Many Colorado Springs patients use Spravato® alongside psychotherapy, medication management, or treatments like TMS.
This coordinated approach supports rapid symptom relief while promoting long-term recovery and emotional stability.
Hear from Our Patients at Southern Colorado TMS!

Cindy – 22
The Southern Colorado TMS Center is truly the most caring, compassionate mental health facility I have ever known. You always hear stories about why people have gone into the mental health field, but these folks truly live it. Everyone who works for SCTMSC (and I mean everyone), exudes warmth and empathy. They walk the walk. One of my family members utilized several of their services, and I got to witness firsthand how they deal with patients. I would highly recommend them to anyone suffering from depression, because they not only offer treatments but expect patients to participate fully in their recovery.

Pam – 25
Dear TMS staff, I want to express my thanks for all your sincere help while I went through a very difficult time. Every time I went to the center the staff was so kind and understanding. The educational classes in the evening were wonderful and I have learned so much about depression. I still look at the handouts you provided. I have gotten into meditation and continue to educate myself about depression and anxiety. If I watch “Friends” on the TV, I will always think of my experience at the Southern Colorado TMS Center!! Thank you for doing your job so well.

Barb – 46
All the staff at SCTMSC are very caring during all of the components of the TMS treatment. From dealing with insurance companies to adjusting one’s treatment time due to conflicts with your schedule; they are all wonderful. I would recommend TMS treatments to any person suffering MDD, as I have for many years. From my experience, TMS helped me far more than an anti-depression medication or CBT.

FB – 35
Dear TMS Team, I just wanted to say that 6 months after treatment, I am doing well. I have a new life and I am living it up. It is like being young again as I am finding my way again. I am so grateful to Dr. Fleming, Camice, Dawn and all the folks who helped me to get here! But especially to Dr Fleming.

Michelle – 37
Dear Dr. Hammock, I am so incredibly grateful and appreciative for all the time and attention you gave to my husband and me. Thank you, thank you for caring so much abut the individual person. I am also grateful that you took the time to help us separate out how we view ourselves in relation to our understanding of God’s love for us verses our symptoms of major depression; neither of us had realized or thought about that. That was incredibly insightful of you and so thoughtful of you to help us get to the root of it. Thank you for helping so many people. I can tell, that you and your team do a lot of good with very sincere hearts. It shines through unmistakably.

Jomaque C
I personally believe TMS should be the first line of treatment for major depressive disorder and generalized anxiety disorder – no medication changes and essentially no side effects! My treatment at Southern Colorado TMS Center is my second round of TMS therapy. The first round resolved my depressive symptoms for several years but when started feeling the depression come back, I knew exactly what to do. Southern Colorado TMS was able to get me scheduled quickly and started with therapy almost immediately. The staff worked on my behalf to have the treatment covered by insurance. I cannot speak highly enough about TMS therapy and Southern Colorado TMS. The therapy has improved my mood in just 8 weeks and the staff are top-notch! I felt welcome on each visit and appreciated the extra touches like a drink and snack after treatment. Southern Colorado TMS Staff – thank you so much for all your help!
Overcome Depression with Spravato in Colorado Springs, CO
Dr. Fleming and our compassionate team at Southern Colorado TMS are ready to help you experience real relief in your treatment-resistant depression. Feel free to give us a call at (719)-220-8655 so we can answer your questions and help you discover whether Spravato is right for you.


